GLP-1 was initially intended for type two diabetics. This medication is secreted by the small intestines in response to nutrient ingestion. Insulin secretion is enhanced from pancreatic beta cells to reduce glucagon cells released ( Filippatos, et all. 2014). GLP-1 has been widely advertised as a weight loss medication by many influencers as well as celebrities, from this there has been a surge in use by many who don't necessarily need this medication. From this reading, there are various side effects from this medication. Many include injection site reactions, upper respiratory and urinary tract infections and even small increases in heart rates. These are a few of the side effects listed, I begin to wonder about the potential long term effects of this use and whether offsprings can be affected as well. As of now there is not much research done for the long term effects but it is interesting to take account of the side effects. Do you or anyone you know use GLP-1 injections and have they experienced any side effects?
Filippatos, T. D., Panagiotopoulou, T. V., & Elisaf, M. S. (2014). Adverse Effects of GLP-1 Receptor Agonists. The review of diabetic studies : RDS, 11(3-4), 202–230. https://doi.org/10.1900/RDS.2014.11.202
GLP-1's are known to be appetite suppressors, so I wonder how blood glucose, electrolytes, and just the overall digestive tract is affected given a person on this medication isnt really eating.
ReplyDeleteGLP-1's are quite interesting! As someone who has diabetes in my family, I wonder if the sudden popularity a year or so ago caused prices for the medicines to skyrocket until they could produce more (a very unfortunate circumstance for many seniors with diabetes who may have limited incomes). Would love to hear more if anyone has any insight!
ReplyDeleteAs someone with multiple obese family members that were on the verge of many health issues due to this, GLP-1's have saved my family. My cousin was at 294 pounds a few months ago and facing hormonal changes, liver damage, joint pain, etc. He has been on GLP-1's for around 2 months and has dropped down to 214 pounds and is a completely different person. Obviously your weight does not define you as a person, but being on this medication has saved my cousin and my aunt is thinking about starting the injections. I guess in my opinion the side effects of the GLP-1's is better than the health risks an individual can face without it.
ReplyDeleteAs someone who personally takes this drug for diabetes and not weight loss, I am so grateful to be on this. I will say, it has been hard to get the drug as now I do not meet the (over)weight requirements, and because this drug dropped my A1c, I am not seen by insurance as a diabetic. This drug has changed my life and the side effects (throwing up, reduced hunger, nausea, other GI problems) have been well worth for the results I get.
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