Friday, October 31, 2025

Think Before You Sip: What Parents Should Know About Sports and Energy Drinks

 We’ve all seen them, some of us probably drink them. Colorful bottles that promise a boost in energy, performance, focus, and hydration. These energy drinks are marketed towards anyone: kids, college students, adults, anyone who is looking for a midday pick me up or for hydration during practices. However, according to the American Academy of Pediatrics, most people, especially kids, don't need them. In fact, they can be harmful. 

Let's begin with the difference between sports and energy drinks:

  • Sports drinks are meant to replace fluids and electrolytes that one loses through sweat during exercise. They contain water, electrolytes, and sugars.

  • Energy drinks are packed with caffeine, other stimulants like guarana, and sugar.

So when are sports drinks actually useful? According to the AAP, they are only needed with intense exercise like marathons, multiple hour practices or when playing in heat (Schneider, 2011). Part of the problem is the intense pressure kids face with performing. As someone who was an athlete as a kid, there was always something that could be done better, you could be faster, stronger, etc. So by being told that with these products you will have better performance, people feel drawn to buying such products. In reality, kids are actually just ingesting unnecessary sugars and calories associated with obesity and tooth decay. As for energy drinks, it is recommended for anyone under the age of 18 to avoid them (Schneider, 2011). This is actually a lot more difficult than it seems given some sports drinks like “Prime” have caffeine in them but it is not clearly displayed.

In the end, the AAP’s message is simple: kids should stick to plain water, hydrate naturally, not chemically.


Questions:

  1. Have you ever noticed a difference after drinking any sports or energy drinks?

  2. Social media influencers have now been making their own products, how have their platforms influenced young people when it comes to buying these products?


Reference:

Marcie Beth Schneider, Holly J. Benjamin, Committee on Nutrition and the Council on Sports Medicine and Fitness; Sports Drinks and Energy Drinks for Children and Adolescents: Are They Appropriate?. Pediatrics June 2011; 127 (6): 1182–1189. 10.1542/peds.2011-0965


Wednesday, October 29, 2025

Are GLP-1 Injections Safe?

 GLP-1 was initially intended for type two diabetics. This medication is secreted by the small intestines in response to nutrient ingestion. Insulin secretion is enhanced from pancreatic beta cells to reduce glucagon cells released ( Filippatos, et all. 2014). GLP-1 has been widely advertised as a weight loss medication by many influencers as well as celebrities, from this there has been a surge in use by many who don't necessarily need this medication. From this reading, there are various side effects from this medication. Many include injection site reactions, upper respiratory and urinary tract infections and even small increases in heart rates. These are a few of the side effects listed, I begin to wonder about the potential long term effects of this use and whether offsprings can be affected as well. As of now there is not much research done for the long term effects but it is interesting to take account of the side effects. Do you or anyone you know use GLP-1 injections and have they experienced any side effects?


Filippatos, T. D., Panagiotopoulou, T. V., & Elisaf, M. S. (2014). Adverse Effects of GLP-1 Receptor Agonists. The review of diabetic studies : RDS, 11(3-4), 202–230. https://doi.org/10.1900/RDS.2014.11.202

Monday, October 20, 2025

I Think I'm "Cool" with Cough Drops.


*COUGH* *COUGH* *COUGH* 

I heard you coughing just now… 

I always have a cherry cough drop in my cherry lunchbox but after hearing (-- actually reading) what I have to say, would you still take this cough drop? The common ingredient that is emphasized in a cough drop is menthol. At your local drugstore, you’d see that plastered on different cough drop brands. 

Thermoreceptors detect temperature but there are certain channels that can detect temperature AND pain. That receptor is TRPM8 and when activated, it triggers sodium channels to open and the sensory neurons (nocioreceptors) to depolarize, which reduces the pain sensation. The cooling effect comes from activating the thermoreceptor. It’s like getting a sprained ankle and icing it to feel relief but in this case, you are “icing your throat.” But when applying ice on our skin, we get a numbing sensation when it’s too cold which indicates that our skin temperature has changed. When we consume menthol, the temperature in our body does not change, it’s an illusion since our thermoreceptors are activated. 

Now, don’t go and take many cough drops to feel the cooling sensation. As everyone knows, too much of something may also be bad for you. There was a case study in India who was diagnosed with menthol poisoning after ingesting peppermint oil. The lethal dose for menthol is around 50-150mg while one cough drop contains 5-10mg (Kumar et al., 2016). Though one may be interested and say that cough drops are yummy, overconsumption of cough drops are not advised. 

Also, let’s say that your cough is caused by a certain disease. Well, cough drops alter the severity of the cough (Johnson et al., 2018), so if you see a provider, make sure to mention that you did take a cough drop. Menthol may increase one’s cough threshold and decrease in cough reflex sensitivity (Wise et al. 2023). So yes, menthol does give you temporary relief but depending on the severity of your cough, it may worsen your symptoms and conditions. 

So would you pass on this cough drop or would you like to take this cough drop and trick your brain to think that everything is “cool”? 



Johnson, D., Mead, R., Kennelty, K., & Hahn, D. (2018). Menthol Cough Drops: Cause for Concern?. Journal of the American Board of Family Medicine : JABFM, 31(2), 183–191. https://doi.org/10.3122/jabfm.2018.02.170363’

Kumar, A., Baitha, U., Aggarwal, P., & Jamshed, N. (2016). A fatal case of menthol poisoning. International journal of applied & basic medical research, 6(2), 137–139. https://doi.org/10.4103/2229-516X.179015

Wise, P. M., Breslin, P. A., & Dalton, P. (2012). Sweet taste and menthol increase cough reflex thresholds. Pulmonary pharmacology & therapeutics, 25(3), 236–241. https://doi.org/10.1016/j.pupt.2012.03.005


Sunday, October 19, 2025

Which Supplements Are Worth Buying?

    Nutrition has always been an interest of mine. Something that has gone alongside that is an interest in supplements. I have spent a lot of time assessing different supplement products and would like to concisely share my personal assessment of which are worth considering, and which are a waste of money. This will be based largely on my own experience and opinion, and I encourage anyone considering adding a supplement to their regimen to do their own research and talk to a doctor first. Most supplements are either a waste of money or can be potentially harmful if used incorrectly. You should also never trust claims that are being made by the same person trying to sell you a product. However, there are some options that are very reasonably priced and are quite affordable. 


    I am a certified personal trainer and have worked in an industry where all sorts of claims are made about products that can sometimes be very expensive. More often than not they are either completely ineffective or priced 400-700% higher than cheaper alternatives that offer the same benefits. There are 4 main categories of supplements that are frequently used. Supplements that promise ergogenic improvement (improvement to physical performance), ones that promise nootropic benefits (support brain health memory, or cognition), ones that support beauty, and those that promise health benefits. Some come with unadvertised health risks whereas others are simply a waste of money. 


    Let's start with ergogenic supplements. Whey Protein powder is very commonly used. It can also be a bit pricey. There is ample evidence that whey protein taken after exercise can have some recovery and anabolic benefits in comparison to other protein sources because of how quickly it is absorbed. However, it is best used after a workout or strenuous activity and should not be routinely used as a meal replacement. The literal scientific standard that all other protein sources are compared to is egg whites. The protein they contain has a complete essential amino acid profile and is very easily absorbed by the body. It is a much more inexpensive alternative to protein shakes and is the superlative form of dietary protein. Whey powders should be reserved for post workout recovery and are not at all necessary but can be a nice luxury. Another type of protein is casein protein. It can be found in whole food sources like cottage cheese but is also available in powder supplement forms. Casein powder is digested slower than other protein sources. This means that people often take it before bed in preparation for being in a fasted state for a longer period of time. Powdered forms can be pricey, but the same benefit can be had from whole food sources. Casein powders aren't a waste of money but don't offer any benefit to cheaper options outside of convenience. The protein market is quite competitive, with razor thin margins for sellers, but is often misused by consumers who use it at less-than-ideal times when they offer no benefit compared to whole food options. 


    There's a long list of supplements that promise ergogenic benefits that are a waste of money. Glutamate, BCAA's, isolated egg yolks. Glutamate is an important amino acid in our body but having a deficiency of it is quite rare. Although it is an important part of many functions of the body, supplementing it simply isn't necessary. BCAA's are similar. They are very important and offer a host of benefits, but they can be found in any animal protein source or eggs, and spending money on isolated BCAA's in a fancy tub from GNC is pretty silly when you already get BCAA's from food. There are also all sorts of strange products like one that is isolated egg yolk. It does contain a nutrient that supports muscle growth and is supported by science, but why not just eat eggs? It offers no benefits over the whole food alternative and is incredibly expensive. These types of supplements take advantage of scientific buzzwords but the actual practice of supplementing them is pretty silly. 


   Nootropic supplements are very interesting. They have the potential to support brain function, memory and cognition. An example of one is Lion's mane. Lion's mane is a mushroom and I'm personally a very big fan of it as a nootropic. It has actually been shown to cause neuron growth and memory enhancement. However, you need to be careful which option you use. Many sources contain just the stems and seeds of the plant, whereas the ones that contain the flowering bodies are much more potent. It is also important to note that any supplement that has the potential to be beneficial could also have potential adverse effects. It is important to review the possible negative effects of Lion's Mane before you were to take it. Another interesting nootropic is Gingko Biloba. I have used Gingko and personally don't notice as dramatic an effect as I do when I take Lion's Mane, but I do feel it has given me a slight mental edge at certain points. It's also important to note that some of these supplements can interfere with medications, particularly psychoactive or psychiatric ones and should be used with extreme caution by anyone taking any kind of antidepressant medication. 


    A supplement that fits into both the Nootropic and ergogenic category is creatine monohydrate. Creatine has well established benefits for physical and cognitive performance. Creatine is directly involved in energy pathways that are used during anaerobic exercise. Not only that but supplementing is able to further support these pathways to produce a positive result. Unlike glutamate and BCAA's which are involved in important pathways in the body, but whose function isn't supported any further through supplementation beyond addressing deficiencies. Creatine is also a very cheap supplement. Creatine seems like a clearly positive option to take. However, it can increase your water intake needs and aggravate preexisting kidney issues. You should be cautious to avoid heat illness and avoid dehydration when taking creatine. There are also many people selling creatine gummies more recently but many of them actually contain very little creatine and are quite expensive. It's probably best to stick to the monohydrate powder form. An interesting side note is that taking creatine with some sugar can help it be better absorbed by your body.


     The beauty and supplement industry is perhaps the most shameless in their outrageous claims of what their product can do. Shampoos and moisturizers contain buzzword compounds that can't even be absorbed through the skin. For example, biotin is well known as a nutrient that supports healthy hair and nails, but it cannot be absorbed through the scalp. Any hair product that includes biotin is just using it as a buzzword. Dietary biotin is an essential part of everyone's diet, although in excess it can cause toxicity that can actually be bad for skin nail and hair health. Collagen is another double-edged sword in the beauty realm of supplements. Collagen powders have little evidence supporting their use. This would make sense as the body breaks down ingested collagen protein into its constituent parts. Your body may or may not use those amino acids to make more collagen, but any other source of protein would also provide all of the amino acids necessary for collagen production. Ingesting collagen supplements doesn't inherently increase the collagen in your body, despite the importance of collagen. You should carefully consider expensive beauty products that use buzzwords but are not supported by science. In most cases, a cheaper whole food option is available. There are some great dietary and dermatological products that support hair skin and nail health such as products containing niacinamide, hyaluronic acid and others. A trick you can use is to look at the ingredients for these products and not just the label and marketing. You will often find that there are much cheaper alternatives to the super lush and overpriced ones that actually contain the same active ingredients. You may find that half the price you are paying for is the celebrity endorsement, packaging and advertisement and not the product itself. 


    Supplements that promise health benefits are about the oldest form of snake oil that swindlers have sold throughout history. Once again many of them do have some benefits but no more so than much less expensive whole food options. An example of this is AG1, a well-advertised supplement that is popular on social media. While it does contain a wide range of high-quality nutrients, it is absurdly expensive for what it includes and simply isn't worth the cost. There is no real justification for buying it when more reasonably priced options exist. Another really interesting example is fish oil. Fish oil is the most popular supplement, by far, with a large industry supported by it and is recommended by many different doctors to their patients. Fish oil is high in an essential fatty acid, omega 3, that is important to have in the diet. However, fish oil can become oxidized very easily. You know that fishy smell of fish oil? It is probably oxidized and could actually have some negative effects on the body. Once again there is a cheaper and more efficient option. Chia seeds are incredibly high in omega 3's and other nutrients like fiber and are much less expensive than fish oil supplements. 


     Overall, it's important to consider the cost benefit analysis of dietary supplements. Many are a complete waste of money, whereas others offer a host of benefits that are well worth it. Whey protein powder, creatine, and nootropics like lion's mane can be a potent and affordable supplement option to add to your diet, but it is important to be careful not to follow the hype of trends or to listen to marketing that would make you believe you need to spend $100's a month on things that have no effect. Emotional advertisements and social media algorithms will try to get you to buy pointless supplements, but it is important to consider the financial and physiological realities objectively before committing to any of them. 







Tuesday, October 7, 2025

BPC 157 The Future?

I was interested in this paper because my father has arthritis, and observing how much it restricts his mobility and daily comfort has always compelled me to learn more about what might be done to treat it. That's why this research on the pentadecapeptide BPC 157 caught my eye immediately. It explores both adjuvant arthritis and NSAID-induced gastrointestinal damage in the rat two issues that are actually very interconnected in human medicine. Pain management in arthritis patients relies on NSAIDs, but the very drugs used to control pain can lead to ulcers and gastrointestinal damage in the long term. What fascinated me most was how BPC 157 seemed to protect the gastrointestinal system but also reduce joint damage as well as inflammation. The scientists tested it with drugs like indomethacin, diclofenac, and aspirin, all of which would typically cause severe ulcers in the stomach of rats under normal circumstances. BPC 157 at even minimal doses (10 pg or 10 ng/kg) greatly blocked the development of ulcers and injury to the intestines That alone is interesting because it suggests BPC 157 may be able to counter one of the most unpleasant side effects of arthritis medications. But the one that truly stunned me was the second half of the experiment the adjuvant arthritis model. The researchers induced arthritis in rats using Freund's adjuvant and afterward treated them with BPC 157 either before, shortly after, or together with the onset of the disease. The result showed that BPC 157 reduced swelling, stiffness, and microscopic evidence of inflammation in the joints. Even when arthritis was already confirmed, BPC 157-treated rats showed clear improvement, and the action persisted after treatment that lasted a year. This indicates that BPC 157 not only inhibits inflammation b ut potentially heals or recovers tissue. The authors speculated that BPC 157 acts by controlling inflammatory mediators like leukotrienes and prostaglandins, which are pivotal in gut damage and arthritis. They even hypothesized that the peptide might have an action on capsaicin-sensitive neurons, those involved in pain transmission as well as mucosal defense. If that is true, BPC 157 may be a link between immune system and neural control something that most anti-inflammatory drugs do not target directly. I think what is interesting about this research is that it is holistic. In contrast to attacking a single symptom or pathway, it considers the systemic mechanism of inflammation, from stomach lining through to joints. That sort of general organ protection may have real clinical benefit, especially for patients like my dad who have difficulty with the cost-benefit calculation between pain relief and side effects. More generally, this paper made me think about how future arthritis treatments might move beyond the suppression of symptoms to body-wide prevention and healing. It raises huge questions: could peptides like BPC 157 eventually replace or augment standard NSAIDs? And if they could, how might they entirely revolutionize the treatment of all chronic inflammatory diseases?


Monday, October 6, 2025

The Safety of Acetaminophen Use During Pregnancy: A Review of Current Evidence

 The moment a woman finds out about a pregnancy, every decision becomes about the unborn baby as well as herself. How do expecting mothers make decisions to keep themselves and their child safe with conflicting information about the potential detriments? The simple answer is to turn to the research and accepted theories based on research and data. While knowing the direct relationship between an individual drug and outcome for a baby is nearly impossible to achieve for a multitude of reasons, researchers have been able to draw conclusions about the safety versus hazard of a multitude of drugs during pregnancy. When determining if any drug is “safe” to take during pregnancy, a drug's potential to cause birth defects is placed into different categories. According to the American Academy of Family Physicians, the FDA has placed drugs into 5 of these categories. In category A drugs, controlled studies did not demonstrate any risk to the fetus, and the possibility of harm is low. In Category B drugs, animal studies have not shown fetal risk, but there have not been human studies conducted OR animal studies have shown adverse effects in the first trimester but no risk in later trimesters. In category C drugs, animal studies have shown adverse fetal effects, or controlled animal/human studies are not available. Category C drugs should only be administered during pregnancy if the benefits outweigh the possible risk to the fetus. In category D drugs, there is evidence of fetal risk related to the use of the drug, but may be used in a life threatening situation where there is no better alternative. The final category is category X. In category X drugs, studies have demonstrated abnormalities and there is no possible benefit which would outweigh the risks. Acetaminophen specifically has been classified as a category B drug. To some, category B may be interpreted as it poses risk, but this is not entirely accurate. A drug can not be classified as category A unless human studies have been done and conclusive to indicate no harm in any trimester. This controlled study can not be conducted for ethical considerations. Category A drugs are limited to vitamins and supplements at this time. When any drug is taken during pregnancy, even those considered category A, women are advised to consult with their providers. Acetaminophen is used as a fever reducer and pain reliever. Its ability to reduce fevers in pregnancy, especially the first trimester, is its most important function. Duke Health has published new evidence that may suggest the long-known theory that fevers, especially in early pregnancy, are directly correlated to some birth defects is more accurate than we initially thought. According to Dr. Eric Benner, a neonatologist and assistant pediatrics professor at Duke, it was previously not known if the virus causing the fever or the fever itself was the source of the potential birth defects, but this new data is indicating that the cause of the fever is neglectable. The actual fever causes harm regardless of source. Also according to Dr. Benner, “The animal models suggest a portion of congenital birth defects in humans might be prevented if fevers are treated through means including the judicious use of acetaminophen during the first trimester.” In their studies, researchers found that neural crest cells, which are critical for the heart, face, and jaw, have temperature sensitive ion channels just like those in sensory cells. Researchers found that when crest cells with TRPV1 and TRPV4 ion channels were placed in fever-like conditions, the embryos subsequently had craniofacial deficits as well as heart defects such as double outlet right ventricle along with other outflow restrictions. In a world where we are so interconnected via the internet, it is more critical than ever for those in power to be distributing accurate information, but also for individuals to take it upon themselves to fact check the information that they receive regardless of the source. 


https://www.aafp.org/pubs/afp/issues/2003/0615/p2517/jcr:content/root/aafp-article-primary-content-container/aafp_article_main_par/aafp_tables_content.print.html 


https://corporate.dukehealth.org/news/how-fever-early-pregnancy-might-cause-heart-facial-birth-defects 


Red Light, Blue Light, or whatever Dr.Seuss said

What if I told you that the reason why it takes so long for you to fall asleep is that you're on your electronics before you go to bed? I mean, it's common sense, right? Well, this paper looked at the effects that different colored lights have on your circadian rhythm and melatonin levels.  The circadian rhythm is like your "internal clock" that regulates your sleep and other physiological processes. But how does it affect the way your body regulates sleep? It's all dependent on the wavelength of the light, where shorter wavelengths disrupt your rhythm more due to the photoreceptor system and the intrinsically photosensitive retinal ganglion cells (ipRGCs). The study found that blue light tends to decrease melatonin production after 2 hours of exposure compared to the red light counterpart. While the study focused on the overall data, they also did some small analyses based on gender, age, and other variables. They found that variation could stem from age-related changes, pupil size, overall health, hormonal levels, and other genetic factors. I thought this was interesting since I did a paper about this topic in high school, which is where I first learned about blue light being emitted from your phone. This topic got me thinking since I realized why blue light glasses were so popular, since they decrease the effect of blue light on your circadian rhythm, but also decrease the amount of headaches you get (I hate staring at my screen for long periods of time). 


Source 

Sanchez-Cano, A., Luesma-Bartolomé, M. J., Solanas, E., & Orduna-Hospital, E. (2025). Comparative Effects of Red and Blue LED Light on Melatonin Levels During Three-Hour Exposure in Healthy Adults. Life15(5), 715. https://doi.org/10.3390/life15050715


Living with C-shaped Scoliosis

 I want to share a little about a condition I have called scoliosis. Scoliosis means that my spine has an abnormal sideways curve. For most people, their spine looks straight when viewed from the front or back, but mine curves in the shape of the letter “C.” This type of curve is called C-shaped scoliosis because there’s just one curve going in one direction instead of two curves like an “S.” Scoliosis affects about 2-3% of the population and usually develops during adolescence, with girls being more likely to have curves that get worse over time (Mayo Clinic).


Doctors don’t know exactly what causes most scoliosis cases the most common type is called idiopathic scoliosis. It often seems to run in families, with genetics contributing to about 30% of the risk, but no one gene causes it (NIAMS). For me, it showed up during my growing years, and girls tend to get it more often than boys.


Having a C-shaped curve means my shoulders and hips can look uneven, and my posture may seem off. Sometimes it causes some discomfort or muscle tightness because one side of my body is a bit more stretched or compressed. Mild scoliosis like mine might not cause pain, but it can lead to muscle fatigue and uneven posture. If the curve gets too severe typically over 45 to 50 degrees it can even make breathing or standing more difficult (OrthoInfo AAOS).


My treatment so far has involved regular check-ups, where doctors monitor the curve through X-rays. If it starts to worsen, they might recommend a brace to prevent progression during growth periods. Stretching and exercise, especially physical therapy approaches like the Schroth Method, help me keep my muscles balanced and manage discomfort. In more extreme cases, surgery such as spinal fusion might be necessary, but I hope it won't come to that.


Living with scoliosis has taught me a lot about paying attention to my body and working with healthcare professionals to keep my spine healthy. It’s not always easy, but with proper management, I believe I can continue to enjoy life and stay active. If anyone else has scoliosis or knows someone who does, you’re not alone, and there are many ways to live well despite the condition.



Adolescent Vaccination Coverage

 A recent CDC report examined vaccination coverage among U.S adolescents ranging from 13-17 years old. This report shed light on what as a society we are excelling at, and most importantly, where adolescents unfortunately fall through the cracks.

It was found that in 2022, over 90% of teens had received the Tdap and MenACWY vaccines but coverage for the HPV vaccine lagged. While most teens would be protected against tetanus, diphtheria, and acellular pertussis, they would be vulnerable to human papillomavirus and its linked cancers. The study makes an interesting connection between COVID-19 and delayed routine vaccinations. With everything being shut down during COVID, especially with stay at home orders in place, vaccine uptake was nearly impossible even for early childhood shots.


Although Tdap and MenACWY uptake has been great, the lag in HPV vaccinations is of concern. This has raised questions about possible barriers of access, awareness, and hesitancy. Especially given that right now medicine is up in the air, the lag in vaccine schedules is bound to get worse. All of this leads me to two questions: 


  1. What do you think are the biggest barriers preventing teens from completing their full HPV vaccine series?

  2. How can schools (very controversial given the timing especially with some states trying to get rid of vaccine mandates), parents, and healthcare providers work together to make up for the lag in vaccinations after the pandemic?


References:
Centers for Disease Control and Prevention. (2020). Decline in child vaccination coverage during the COVID-19 pandemic — United States, 2020. Morbidity and Mortality Weekly Report, 69(20), 625–626. https://www.cdc.gov/mmwr/volumes/69/wr/mm6920e1.htm

Centers for Disease Control and Prevention. (2024). Health and economic benefits of routine childhood immunizations — United States, 2023. Morbidity and Mortality Weekly Report, 73(31), 1011–1016. https://www.cdc.gov/mmwr/volumes/73/wr/mm7331a2.htm

DMS Skincare Can Mimic Lipid Structure!

What is Derma Membrane Structure (DMS)? 

DMS is a technology used in skincare that creates topical creams with a lamellar structure that mimics the natural lipid barrier of the skin to promote repair. What makes this topical cream different from other skin emulsifiers, is that it contains physiological lipids like ceramides, cholesterol, and free fatty acids. These 3 ingredients resemble the natural lipids found in the the skins outermost epidermis layer (stratum corneum) (Schild et al., 2024; Berdyshev, 2024).

Stress and the Immune System

     As someone who grew up with several food and environmental allergies, I grew a significant interest in the immune system and why my body reacts the way it does to viruses as well as some foods. In my undergraduate studies, I have chosen to pursue immunology research as well, learning more about some of the proteins and transcription factors related to the allergic response.

    As academic pressure starts to build approaching midterms, I started to think about how chronic stress can affect our immune systems. In reflection, I recognize that illness starts to peak around heavy exam weeks, and I notice some of my peers experience frequent viruses when they don’t get enough sleep for a prolonged period of time. 

    We likely have all heard our teachers and professors advise us to get quality sleep and a good breakfast before a significant exam, but sometimes that advice can feel hard to follow when the reasoning behind it is misunderstood. Sometimes the natural instinct is to attempt to stay up late to cram more information.

    In the short term, stress can increase our innate immune response, which is our more immediate non-adaptive immune response. More specifically, the activity of natural killer cells and inflammatory chemical messengers (cytokines) is enhanced by acute stress. However, chronic stress can have a suppressing effect on the immune system. More specifically, studies suggest that our T cells (considered the helper cells of adaptive immunity) have a decrease in activation and proliferation in cases of chronic stress. Research also suggests that insomnia causes HPA dysregulation, which affects the immune system by decreasing lymphocyte proliferation in response to vaccinations. 

    What this means is that, in the situation of heavy exam weeks, students who experience chronic stress during exam week have a weakened immune system, ultimately making it harder to fight off some of the viruses that circle around. Therefore, managing psychological stress and physiological stress (such as lack of sleep and lack of nutrition) as much as possible during exam weeks can help to prevent getting sick.

References:

Alotiby, A. (2024). Immunology of stress: A review article. Journal of Clinical Medicine, 13(21), 6394. 

https://doi.org/10.3390/jcm13216394 

Ince, L. M., Weber, J., & Scheiermann, C. (2019). Control of leukocyte trafficking by stress-associated 

hormones. Frontiers in Immunology, 9. https://doi.org/10.3389/fimmu.2018.03143 

Reed, R. G., & Raison, C. L. (2016). Stress and the immune system. Environmental Influences on the 

Immune System, 97–126. https://doi.org/10.1007/978-3-7091-1890-0_5 

Seiler, A., Fagundes, C. P., & Christian, L. M. (2019). The impact of everyday stressors on the immune 

system and health. Stress Challenges and Immunity in Space, 71–92. 

https://doi.org/10.1007/978-3-030-16996-1_6 

Zhang, X., Zink, F., Hezel, F., Vogt, J., Wachter, U., Wepler, M., Loconte, M., Kranz, C., Hellmann, 

A., Mizaikoff, B., Radermacher, P., & Hartmann, C. (2020). Metabolic substrate utilization in 

stress-induced immune cells. Intensive Care Medicine Experimental, 8(S1). 

https://doi.org/10.1186/s40635-020-00316-0 


Sunday, October 5, 2025

You Are What You Eat

 In recent years, studies have hinted at a possible correlation between our gut microbiome, and mental health. While stress and anxiety are typically addressed through psychological or pharmaceutical contexts, recent studies suggest the microbiota in our gut are influential in managing these conditions. This concept is called the gut-brain axis, which is a two-way communication system linking the central nervous system and the gastrointestinal tract. Imbalances of bacteria in our gut (dysbiosis) can disrupt the production of key neurotransmitters like serotonin, dopamine, and GABA, (Kumar et al. 2023), which regulate mood. These imbalances can increase inflammation in the body and stress responses, which contribute to symptoms of anxiety and depression. 


In the context of western health, the leading cause of dysbiosis is the Western diet. The Western diet consists of highly processed foods, saturated fats, refined sugars, and low fiber, which promotes inflammation, reduces microbial diversity, and weakens the gut barrier (CClemente-Suarez et al 2023). These changes in the gut biome ultimately impair gut-brian signaling and contribute to oxidative stress and neuroinflammation, both of which are linked to mental health disorders. However, an unhealthy microbiome is not limited to mental health. 


Research shows that gut microbes also produce compounds like TMAO, which are associated with cardiovascular disease (Tang et at. 2017), thus highlighting the microbiome's far-reaching impact on overall health and well-being. Additional health concerns that stem from an unhealthy microbiome include chronic stress, poor metabolic function, and heart disease - all of which create a feedback loop worsened by poor diet and microbial imbalance. However, our guts are extremely adaptable and increasing the intake of fiber-rich foods, fermented products (i.e greek yogurt), and plant-based nutrients can help restore a person’s gut microbiome.


By restoring balance in your microbiome, you can help improve digestion, which improves nutrient absorption, leading to a stronger immune system, which helps reduce inflammation, ultimately improving cardiovascular health. Additionally, in recent years, psychobiotics are being studied for their ability to directly influence emotional health (Kumar et at. 2023) - a topic for another day. 


It is needless to say that what we eat has profound effects on how we feel, and supporting a healthy gut through cleaner dietary choices may offer a powerful tool for managing stress and anxiety.


Works Cited:

Clemente-Suárez, V. J., Beltrán-Velasco, A. I., Redondo-Flórez, L., Martín-Rodríguez, A., & Tornero-Aguilera, J. F. (2023). Global Impacts of Western Diet and Its Effects on Metabolism and Health: A Narrative Review. Nutrients, 15(12), 2749. https://doi.org/10.3390/nu15122749


Kumar, A., Pramanik, J., Goyal, N., Chauhan, D., Sivamaruthi, B. S., Prajapati, B. G., & Chaiyasut, C. (2023). Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options. Pharmaceuticals (Basel, Switzerland), 16(4), 565. https://doi.org/10.3390/ph16040565


Lewandowska-Pietruszka, Z., Figlerowicz, M., & Mazur-Melewska, K. (2022). The History of the Intestinal Microbiota and the Gut-Brain Axis. Pathogens (Basel, Switzerland), 11(12), 1540. https://doi.org/10.3390/pathogens11121540


Bass in Music, Emotion and Physiological Impacts

   When you go to a concert and lose yourself in the music and describe it as an out of body experience? Once you go home are your ears ringing and numb for the next two days but totally worth it? Although live concert events are amazing opportunities to see beloved artists, hang out with friends or just have a fun time there are serious consequences due to the dangerous volume levels. Granted, not everyone goes to concerts frequently but there can be alternatives  established to keep volumes safe and listeners immersed. 

  Researchers found that the bass allows listeners to become more immersed. Increasing the bass won't turn a song into a hit or a party anthem but if the song is meant to be high energy the bass can take the song up a notch without raising overall volume. 


  The brain's immediate reaction to more bass has zero effect, pathways did not care for more bass, but there more was response to the bass over time as the song continued. There is a weak but statistically significant effect in low brain waves, the brain was using the bass to lock into/engage into the music more as the song progressed. Strong vibrations (feeling the bass) can activate the vestibular system (balance system in inner ear), when the powerful bass hits the body, a whole other system is involved within the sense of space and stability (hear, balance and touch) contributing to the overall immersive feeling (Epain et al., 2025). Bass amplification does effectively enhance the emotional experience of music, especially the feelings of overall energy and excitement. This leads me to wonder what concerts could potentially look like if music was lowered at concerts but was still lively enough to keep listeners engaged while protecting hearing. Would you still attend these events? 


References 
Epain, N. E., Moulin, S., Mingam, C., Wallerich, M., Corteel , E., & Arnal , Luc. H. (2025, January 5). Bass amplification impacts emotional, neural and physiological responses to music. Science Direct. https://www.sciencedirect.com/science/article/am/pii/S1879729619301437

Circular Breathing for Musicians

    You may wonder how a wind instrument player can play impressively long notes. Most people believe that it's just an increase in lug capacity. This may play a part for most musicians, but for the far more advanced and professional performers, they practice what is called circular breathing. This is a technique where the musician expels air through the mouth (playing their instrument) while intaking breath through the nose. This happened by expelling air via cheek compression in the anterior oropharynx during nasal inhalation, which simulates the lungs refilling (Peng et. Al, 2015). This practice is very hard for musicians to master, or even attempt. I have played the Trumpet for 12 years, and I have yet to successfully perform this technique. The specific physiology of circular breathing involves the posterior tongue and the velopharynx. The velopharynx is typically thought to be a structure that can't be voluntarily controlled by humans because of how the pharyngeal restrictors but because of the increased pressure at the back of the mouth by the cheeks, this may be able to cause voluntary movement (Peng et. Al, 2015)

    Circular breathing is not only helpful for playing concertos and jazz charts, but it has also been shown to help with obstructive sleep apnea. Research shows that breath therapy using a rather odd instrument called a didgeridoo can help reduce sleep apnea, which overall improves a person's sleep, which leads to less daytime drowsiness, along with other benefits (Peng et. Al, 2015). Perhaps we all should include some didgeridoo-ing in our day-to-day lives to improve our sleep quality and air intake!




Peng, T., Phillips, C. D., Dyke, J. P., & Stewart, M. G. (2015). Mechanics of circular breathing in wind musicians using cine magnetic resonance imaging techniques. The Laryngoscope, 125(2), 412–418. https://doi-org.dml.regis.edu/10.1002/lary.24928

Why do I still feel sore after 2 days?

 Why do I still feel sore after 2 days?

Understanding the Physiology of delayed onset muscle soreness (DOMS)


Have you ever had a really extreme workout, felt fine but a day or two later you felt like you couldn’t even move? That delayed soreness is not bad luck, it's more so normal and how our bodies adapt to new exercise stress, which is a process called Delayed-Onset Muscle soreness (DOMS).


DOMS develops when a specific muscle group performs unaccustomed or strenuous activity, especially movements that the body isn’t used to (Robinson & Wakefield 2010). This can happen to literally anyone whether it’s professional athletes or people who just like to go to the gym. That soreness begins within 12-24 hours and usually peaks on day two, which is why you still feel that soreness and usually even feel worse on day two. 


DOMS results from a disruption of muscle fibrils, at the myotendinous junction which is where muscle fibers attach to tendons (Robinson & Wakefield 2010). That region has a lot of pain receptors, and it results from ultrastructural damage to muscle fibers when pushed beyond their usual load (Schroeter et al., 2024). The damage that’s done is usually harmless because it heals within a few days, but during this phase the muscles will suffer from stiffness, decline in performance and an increased injury risk. It is classified as a Type 1b muscle injury, a delayed onset muscle pain which is distinct from the severe muscle strains (Schroeter et al., 2024). 


There are many approaches to manage DOMS, including starting with lighter and lower loads and increasing slowly to prevent micro damage or heat therapy could alleviate the muscle tension by increasing blood flow (Schroeter et al., 2024). When you feel sore and stiff two days post workout, it is a normal response.






References 

UPDATE Delayed Onset Muscle Soreness (DOMS) – Muscle Biomechanics, Pathophysiology and Therapeutic Approaches. (2024). Germanjournalsportsmedicine.com. https://www.germanjournalsportsmedicine.com/archive/archive-2024/issue-5/update-delayed-onset-muscle-soreness-doms-muscle-biomechanics-pathophysiology-and-therapeutic-approaches/


  Robinson, Philip, and Richard J Wakefield. “Muscle.” Elsevier EBooks, 1 Jan. 2010, pp. 137–151, https://doi.org/10.1016/b978-1-4377-0127-2.10012-7.


Chasing the high with Horror Games

 

    I like to play video games, but have sparingly played the horror variety. This is only because I am a coward and do not want to play them, but one of my friends mentioned how they play them daily for the feeling of being scared. They spoke about this feeling comparable to riding on a roller coaster, which made me curious if there was any actually studies done around the effect of horror games physiologically. I came across many studies, but there was a distinction that I noticed between the different types of horror games. I was not very well versed with the horror genre, so I never even thought about how a VR horror games could affect you versus one on a computer. The study surrounding the VR horror games did not go too in depth in the physiological side of things, but does open up the idea of different types of fear someone could experience while playing a horror game. For example, the fear of being chased would motivate someone to run, while seeing something scary might motivate the player to keep watching in some sort of messed up way.

    There is also the idea that many companies know of this addictive feeling of fear because it could trigger adrenaline in the player. One study wanted to study the specific stimulus-organism-response (S-O-R) that players experience, but discovered the importance of emotional value in these types of games. Through using this method of research, they were able to discover the game designs that would impact a players perceived control and play intention in a way to target their emotions. Balancing the controls and intentions a player can have while also including the fear aspects becomes a sort of balance that companies try to perfect to make a game the right amount of addicting. If a player doesn't have enough control, or if the fear content is more frustrating than actually scary, they could lose players because they aren't getting the horror game high. 

    Horror videos games seem to try and create the perfect atmosphere to give their players the addicting feeling of adrenaline with many different forms of stimulus. Currently, there is not an issue with this system. There is not video game who has been able to keep the same adrenaline high once a player gets used to it, which leads to companies still developing more and more horror games. If a company was ever able to perfect a horror game where people were able to always get an adrenaline high from it, they could theoretically form an actual addiction even worse than what players can have for video games right now. 


References

Nemeth, K., & Szucs, J. (2024). Gaming Under Stress: Sensor-Monitored Physiological Responses to a            Horror Gameplay. 2024 IEEE 28th International Conference on Intelligent Engineering                          Systems (INES), Intelligent Engineering Systems (INES), 2024 IEEE 28th International                           Conference On, 000059–000064. https://doiorg.dml.regis.edu/10.1109/INES63318.2024.10629131

Zhang, H., Li, X., Fu, X., Qiu, C., Zhang, J., & Carroll, J. M. (2024). Understanding Fear Responses and Coping Mechanisms in VR Horror Gaming: Insights From Semistructured Interviews. IEEE Transactions on Games, Games, IEEE Transactions on, IEEE Trans. Games, 16(4), 868–881. https://doi-org.dml.regis.edu/10.1109/TG.2024.3403768

Savino, K. N. N., Mateo, R. A. B., & Ong, A. K. S. (2025). Chasing the Rush: How horror games trigger adrenaline and fuel Fear-Inducing elements. Entertainment Computing, 55. https://doi-org.dml.regis.edu/10.1016/j.entcom.2025.101001

Behind Smelling Salts

  If you’ve ever watched powerlifters, athletes or even old movies where someone faints, you’ve probably seen smelling salts make an appeara...